New Results
Human knockouts in a cohort with a high rate of consanguinity
Danesh Saleheen, View ORCID ProfilePradeep Natarajan, View ORCID ProfileWei Zhao, View ORCID ProfileAsif Rasheed, View ORCID ProfileSumeet Khetarpal, View ORCID ProfileHong-Hee Won, View ORCID ProfileKonrad J. Karczewski, View ORCID ProfileAnne H O’Donnell-Luria, View ORCID ProfileKaitlin E. Samocha, View ORCID ProfileNamrata Gupta, View ORCID ProfileMozzam Zaidi, View ORCID ProfileMaria Samuel, View ORCID ProfileAtif Imran, View ORCID ProfileShahid Abbas, View ORCID ProfileFaisal Majeed, View ORCID ProfileMadiha Ishaq, View ORCID ProfileSaba Akhtar, View ORCID ProfileKevin Trindade, View ORCID ProfileMegan Mucksavage, View ORCID ProfileNadeem Qamar, View ORCID ProfileKhan Shah Zaman, View ORCID ProfileZia Yaqoob, View ORCID ProfileTahir Saghir, View ORCID ProfileSyed Nadeem Hasan Rizvi, View ORCID ProfileAnis Memon, View ORCID ProfileNadeem Hayyat Mallick, View ORCID ProfileMohammad Ishaq, View ORCID ProfileSyed Zahed Rasheed, View ORCID ProfileFazal-ur-Rehman Memon, View ORCID ProfileKhalid Mahmood, View ORCID ProfileNaveeduddin Ahmed, View ORCID ProfileRon Do, View ORCID ProfileDaniel G. MacArthur, View ORCID ProfileStacey Gabriel, View ORCID ProfileEric S. Lander, View ORCID ProfileMark J. Daly, View ORCID ProfilePhilippe Frossard, View ORCID ProfileJohn Danesh, View ORCID ProfileDaniel J. Rader, View ORCID ProfileSekar Kathiresan
doi: https://doi.org/10.1101/031518
Danesh Saleheen
1Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
2Center for Non-Communicable Diseases, Karachi, Pakistan
Pradeep Natarajan
3Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Wei Zhao
1Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Asif Rasheed
2Center for Non-Communicable Diseases, Karachi, Pakistan
Sumeet Khetarpal
5Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Hong-Hee Won
3Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Konrad J. Karczewski
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Anne H O’Donnell-Luria
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
7Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
Kaitlin E. Samocha
6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Namrata Gupta
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Mozzam Zaidi
2Center for Non-Communicable Diseases, Karachi, Pakistan
Maria Samuel
2Center for Non-Communicable Diseases, Karachi, Pakistan
Atif Imran
2Center for Non-Communicable Diseases, Karachi, Pakistan
Shahid Abbas
8Faisalabad Institute of Cardiology, Faisalabad, Pakistan
Faisal Majeed
2Center for Non-Communicable Diseases, Karachi, Pakistan
Madiha Ishaq
2Center for Non-Communicable Diseases, Karachi, Pakistan
Saba Akhtar
2Center for Non-Communicable Diseases, Karachi, Pakistan
Kevin Trindade
5Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Megan Mucksavage
5Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Nadeem Qamar
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Khan Shah Zaman
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Zia Yaqoob
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Tahir Saghir
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Syed Nadeem Hasan Rizvi
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Anis Memon
9National Institute of Cardiovascular Disorders, Karachi, Pakistan
Nadeem Hayyat Mallick
10Punjab Institute of Cardiology, Lahore, Pakistan
Mohammad Ishaq
11Karachi Institute of Heart Diseases, Karachi, Pakistan
Syed Zahed Rasheed
11Karachi Institute of Heart Diseases, Karachi, Pakistan
Fazal-ur-Rehman Memon
12Red Crescent Institute of Cardiology, Hyderabad, Pakistan
Khalid Mahmood
13The Civil Hospital, Karachi, Pakistan
Naveeduddin Ahmed
14Liaquat National Hospital, Karachi, Pakistan
Ron Do
15Department of Genetics and Genomic Sciences, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA
16The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Daniel G. MacArthur
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Stacey Gabriel
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Eric S. Lander
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Mark J. Daly
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
6Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Philippe Frossard
2Center for Non-Communicable Diseases, Karachi, Pakistan
John Danesh
17Department of Public Health and Primary Care, University of Cambridge, UK
18Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
Daniel J. Rader
5Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
19Department of Human Genetics, University of Pennsylvania, USA
Sekar Kathiresan
3Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA
4Broad Institute of Harvard and MIT, Cambridge, MA, USA
Article usage
Posted November 12, 2015.
Human knockouts in a cohort with a high rate of consanguinity
Danesh Saleheen, Pradeep Natarajan, Wei Zhao, Asif Rasheed, Sumeet Khetarpal, Hong-Hee Won, Konrad J. Karczewski, Anne H O’Donnell-Luria, Kaitlin E. Samocha, Namrata Gupta, Mozzam Zaidi, Maria Samuel, Atif Imran, Shahid Abbas, Faisal Majeed, Madiha Ishaq, Saba Akhtar, Kevin Trindade, Megan Mucksavage, Nadeem Qamar, Khan Shah Zaman, Zia Yaqoob, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Nadeem Hayyat Mallick, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-ur-Rehman Memon, Khalid Mahmood, Naveeduddin Ahmed, Ron Do, Daniel G. MacArthur, Stacey Gabriel, Eric S. Lander, Mark J. Daly, Philippe Frossard, John Danesh, Daniel J. Rader, Sekar Kathiresan
bioRxiv 031518; doi: https://doi.org/10.1101/031518
Human knockouts in a cohort with a high rate of consanguinity
Danesh Saleheen, Pradeep Natarajan, Wei Zhao, Asif Rasheed, Sumeet Khetarpal, Hong-Hee Won, Konrad J. Karczewski, Anne H O’Donnell-Luria, Kaitlin E. Samocha, Namrata Gupta, Mozzam Zaidi, Maria Samuel, Atif Imran, Shahid Abbas, Faisal Majeed, Madiha Ishaq, Saba Akhtar, Kevin Trindade, Megan Mucksavage, Nadeem Qamar, Khan Shah Zaman, Zia Yaqoob, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Nadeem Hayyat Mallick, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-ur-Rehman Memon, Khalid Mahmood, Naveeduddin Ahmed, Ron Do, Daniel G. MacArthur, Stacey Gabriel, Eric S. Lander, Mark J. Daly, Philippe Frossard, John Danesh, Daniel J. Rader, Sekar Kathiresan
bioRxiv 031518; doi: https://doi.org/10.1101/031518
Subject Area
Subject Areas
- Biochemistry (11697)
- Bioengineering (8714)
- Bioinformatics (29110)
- Biophysics (14921)
- Cancer Biology (12045)
- Cell Biology (17347)
- Clinical Trials (138)
- Developmental Biology (9404)
- Ecology (14133)
- Epidemiology (2067)
- Evolutionary Biology (18260)
- Genetics (12214)
- Genomics (16758)
- Immunology (11838)
- Microbiology (27985)
- Molecular Biology (11543)
- Neuroscience (60766)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3224)
- Physiology (4934)
- Plant Biology (10379)
- Synthetic Biology (2876)
- Systems Biology (7331)
- Zoology (1640)