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- July 8, 2015.
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- 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels väg 12 A, SE-17 177, Stockholm, Sweden
- 2MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crew Road, EH4 2XU, Edinburgh, UK
- 3Novosibirsk State University, Pirogova 2, 630090, Novosibirsk, Russia
- 4Institute of Cytology and Genetics SB RAS, Lavrentyeva ave. 10, 630090, Novosibirsk, Russia
- 5Centre for Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG, United Kingdom
- 6PolyOmica, De Savornin Lohmanlaan 19a, 9722, Groningen, The Netherlands
- 7Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrheniusväg 20 C, SE-10 691, Stockholm, Sweden
- 8The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, United Kingdom
- 9Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraβe 1, 85764 Oberschleiβheim, Germany
- 10Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK
- 11Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK
- 12Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK
- 13Division of Population Health Sciences, University of Dundee, Dundee, UK
- 14Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK
- 15Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
- ↵*Corresponding authors:
Correspondence should be addressed to xia.shen{at}ki.se and y.s.aulchenko{at}polyomica.com.
Contributions: Initiated and coordinated the study
Developed statistical methods
Analyzed the data
Investigated candidate genes
Contributed to replication analysis
Contributed replication data
Supervised the study
Contributed to writing
↵† These authors contributed equally to this work.