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Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping
View ORCID ProfileChris Wallace, View ORCID ProfileAntony J Cutler, View ORCID ProfileNikolas Pontikos, View ORCID ProfileMarcin L Pekalski, View ORCID ProfileOliver S Burren, View ORCID ProfileJason D Cooper, View ORCID ProfileArcadio Rubio García, View ORCID ProfileRicardo C Ferreira, View ORCID ProfileHui Guo, View ORCID ProfileNeil M Walker, View ORCID ProfileDeborah J Smyth, View ORCID ProfileStephen S Rich, View ORCID ProfileSuna Onengut-Gumuscu, View ORCID ProfileStephen J Sawcer, View ORCID ProfileMaria Ban, View ORCID ProfileSylvia Richardson, View ORCID ProfileJohn A Todd, View ORCID ProfileLinda S Wicker
doi: https://doi.org/10.1101/015164
Chris Wallace
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
2MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK
Antony J Cutler
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Nikolas Pontikos
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Marcin L Pekalski
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Oliver S Burren
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Jason D Cooper
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Arcadio Rubio García
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Ricardo C Ferreira
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Hui Guo
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
4Centre for Biostatistics Institute of Population Health The University of Manchester Room 1.308, Jean McFarlane Building Oxford Road Manchester M13 9PL
Neil M Walker
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Deborah J Smyth
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Stephen S Rich
5Center for Public Health Genomics, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, VA, USA
6Department of Medicine, Division of Endocrinology, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, VA, USA
Suna Onengut-Gumuscu
5Center for Public Health Genomics, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, VA, USA
7Department of Public Health Sciences, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, VA, USA
Stephen J Sawcer
8University of Cambridge, Department of Clinical Neurosciences, Box 165, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK
Maria Ban
8University of Cambridge, Department of Clinical Neurosciences, Box 165, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK
Sylvia Richardson
2MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK
John A Todd
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Linda S Wicker
1JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Research Campus, Cambridge, CB2 0XY, UK
Article usage
Posted June 01, 2015.
Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping
Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, Jason D Cooper, Arcadio Rubio García, Ricardo C Ferreira, Hui Guo, Neil M Walker, Deborah J Smyth, Stephen S Rich, Suna Onengut-Gumuscu, Stephen J Sawcer, Maria Ban, Sylvia Richardson, John A Todd, Linda S Wicker
bioRxiv 015164; doi: https://doi.org/10.1101/015164
Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping
Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, Jason D Cooper, Arcadio Rubio García, Ricardo C Ferreira, Hui Guo, Neil M Walker, Deborah J Smyth, Stephen S Rich, Suna Onengut-Gumuscu, Stephen J Sawcer, Maria Ban, Sylvia Richardson, John A Todd, Linda S Wicker
bioRxiv 015164; doi: https://doi.org/10.1101/015164
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