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LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies
View ORCID ProfileBrendan K. Bulik-Sullivan, Po-Ru Loh, Hilary Finucane, Stephan Ripke, Jian Yang, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Nick Patterson, Mark J. Daly, Alkes L. Price, Benjamin M. Neale
doi: https://doi.org/10.1101/002931
Brendan K. Bulik-Sullivan
1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA
2Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA
Po-Ru Loh
4Department of Epidemiology, Harvard School of Public Health, Boston, MA
5Department of Biostatistics, Harvard School of Public Health, Boston, MA
Hilary Finucane
6Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA
Stephan Ripke
2Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA
Jian Yang
7Brain Institute, University of Queensland, Brisbane, Queensland, Australia
8University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nick Patterson
1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA
Mark J. Daly
1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA
2Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA
Alkes L. Price
1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA
4Department of Epidemiology, Harvard School of Public Health, Boston, MA
5Department of Biostatistics, Harvard School of Public Health, Boston, MA
Benjamin M. Neale
1Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA
2Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA
Article usage
Posted February 21, 2014.
LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies
Brendan K. Bulik-Sullivan, Po-Ru Loh, Hilary Finucane, Stephan Ripke, Jian Yang, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Nick Patterson, Mark J. Daly, Alkes L. Price, Benjamin M. Neale
bioRxiv 002931; doi: https://doi.org/10.1101/002931
LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies
Brendan K. Bulik-Sullivan, Po-Ru Loh, Hilary Finucane, Stephan Ripke, Jian Yang, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Nick Patterson, Mark J. Daly, Alkes L. Price, Benjamin M. Neale
bioRxiv 002931; doi: https://doi.org/10.1101/002931
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