Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
Constantine N. Tzouanas, Marc S. Sherman, Jessica E.S. Shay, Adam J. Rubin, Benjamin E. Mead, Tyler T. Dao, Titus Butzlaff, Miyeko D. Mana, Kellie E. Kolb, Chad Walesky, Brian J. Pepe-Mooney, Colton J. Smith, Sanjay M. Prakadan, Michelle L. Ramseier, Evelyn Y. Tong, Julia Joung, Fangtao Chi, Thomas McMahon-Skates, Carolyn L. Winston, Woo-Jeong Jeong, Katherine J. Aney, Ethan Chen, Sahar Nissim, Feng Zhang, Vikram Deshpande, Georg M. Lauer, Ömer H. Yilmaz, Wolfram Goessling, Alex K. Shalek
bioRxiv 2023.11.30.569407; doi: https://doi.org/10.1101/2023.11.30.569407