Abstract
Biocircuit modeling sometimes requires explicit tracking of a self-replicating DNA species. The most obvious, straightforward way to model a replicating DNA is structurally unstable and leads to pathological model behavior. We describe a simple, stable replication mechanism with good model behavior and show how to derive it from a mechanistic model of ColE1 replication.
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
↵∗ E-mail: murray{at}cds.caltech.edu
Copyright
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