Abstract
Summary We present NewWave, a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA sequencing data. To achieve scalability, NewWave uses mini-batch optimization and can work with out-of-memory data, enabling users to analyze datasets with millions of cells.
Availability and implementation NewWave is implemented as an open-source R package available through the Bioconductor project at https://bioconductor.org/packages/NewWave/
Supplementary information Supplementary data are available at Bioinformatics online.
Competing Interest Statement
The authors have declared no competing interest.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.