Abstract
UCell is an R package for evaluating gene signatures in single-cell datasets. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation demands less computing time and memory than other available methods, enabling the processing of large datasets in a few minutes even on machines with limited computing power. UCell can be applied to any single-cell data matrix, and includes functions to directly interact with Seurat objects. The UCell package and documentation are available on GitHub at https://github.com/carmonalab/UCell
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
(Massimo.Andreatta{at}unil.ch)
(Santiago.Carmona{at}unil.ch)
Copyright
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