Abstract
The ability to measure synaptic connectivity and properties is essential for understanding of neuronal circuits. However, the existing methods that allow such measurements at cellular resolution are laborious and technically demanding. Here we describe a system that allows such measurements in a high-throughput way by combining concurrent two-photon optogenetics and volumetric Ca2+ imaging with whole-cell recording, and reveal in zebrafish a circuit motif for generating fast undulatory locomotion.
Copyright
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