Abstract
Clostridioides difficile has become the leading cause of hospital-acquired diarrhea. Clindamycin is a member of the macrolide-lincosamide-streptogramin B family of protein synthesis inhibitors. Been the ribosomal methylation the most widespread mechanism of resistance to these antibiotics in C difficile erm genes usually produce high levels of resistance to these drugs. In this short report we present evidence about the presence of an unreported putative erm gene in C difficile isolates that despite of presenting a ΔermB genotype maintain high levels of clindamycin resistance.
Competing Interest Statement
The authors have declared no competing interest.
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